MySQL是一個常用的關系型數據庫管理系統。在使用MySQL時，我們常常會遇到需要將多個列去重的情況。下面介紹幾種方法實現。

1. 使用DISTINCT
SELECT DISTINCT column1, column2, column3 FROM table_name;
2. 使用GROUP BY
SELECT column1, column2, column3 FROM table_name GROUP BY column1, column2, column3;
3. 使用子查詢
SELECT column1, column2, column3 FROM table_name WHERE (column1, column2, column3) IN (SELECT column1, column2, column3 FROM table_name GROUP BY column1, column2, column3);
4. 使用UNION
SELECT column1, column2, column3 FROM table_name1 UNION SELECT column1, column2, column3 FROM table_name2;
5. 使用INNER JOIN
SELECT table1.column1, table1.column2, table1.column3 FROM table_name1 table1 INNER JOIN table_name2 table2 ON table1.column1 = table2.column1 AND table1.column2 = table2.column2 AND table1.column3 = table2.column3;
6. 使用ROW_NUMBER()
SELECT column1, column2, column3 FROM ( SELECT column1, column2, column3, ROW_NUMBER() OVER (PARTITION BY column1, column2, column3 ORDER BY column1, column2, column3) rowid FROM table_name ) t WHERE t.rowid = 1;

以上是幾種常用的方法來實現MySQL中多列去重操作。根據具體情況選擇不同的方法。希望對大家有幫助。